Which dosage form is generally a water-base preparation applied to wet surfaces?

• A. Paste
• B. Transdermal
• C. Cream
• D. Ointment

Answer: (C)

Water-based topical forms are designed to spread easily on moist surfaces and to be easily washed away. Creams fit this description because they are semisolid emulsions with a substantial aqueous phase, making them hydrophilic and less greasy. This water content allows a creamy layer to coat wet skin or surfaces without a heavy, occlusive feel, and it can be removed with water. In contrast, pastes are thick with high solid content, ointments are oil-based and greasy, and transdermal preparations are designed for sustained drug delivery through the skin rather than application to wet surfaces. So, the best fit for a water-base preparation applied to wet surfaces is a cream.