Which medication is an antiemetic?

Prepare thoroughly for the MDC Pharmacokinetics Exam with our detailed guidance. Utilize flashcards and multiple-choice questions, complete with hints and explanations, to excel in your test!

Multiple Choice

Which medication is an antiemetic?

Explanation:
Meclizine is an antiemetic because it blocks histamine H1 receptors, especially in the vestibular system and vomiting pathways. This action dampens the signals from the inner ear that trigger nausea and vomiting, making it especially effective for motion sickness and vertigo. While the other drugs listed can also reduce nausea—ondansetron inhibits 5-HT3 receptors, promethazine is an H1 blocker with antiemetic effects, and metoclopramide is a D2 antagonist with prokinetic action—the classic choice for preventing motion-induced nausea is an antihistamine like meclizine, which directly targets the vestibular input that commonly causes symptoms.

Meclizine is an antiemetic because it blocks histamine H1 receptors, especially in the vestibular system and vomiting pathways. This action dampens the signals from the inner ear that trigger nausea and vomiting, making it especially effective for motion sickness and vertigo. While the other drugs listed can also reduce nausea—ondansetron inhibits 5-HT3 receptors, promethazine is an H1 blocker with antiemetic effects, and metoclopramide is a D2 antagonist with prokinetic action—the classic choice for preventing motion-induced nausea is an antihistamine like meclizine, which directly targets the vestibular input that commonly causes symptoms.

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